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JAGI Module | Joint, Autoimmune, Gut & Inflammation Care in Walnut Creek, CA

JAGI Module

The JAGI Module is MIHA's dedicated program for chronic disease outside the "big three" conditions that account for most chronic illness in the industrialized world — cardio-arteriometabolic disease, aberrant cell growth, and neurodegeneration. JAGI stands for Joint, Autoimmune, Gut, and Inflammation: it investigates the inflammatory and autoimmune states that cause loss of function and increased pain signaling throughout the body, most visibly as joint degeneration and arthritis.

Get to the Root of Chronic Pain and Inflammation

Joint pain, autoimmune flare-ups, and digestive issues can feel like unrelated problems, but they're often connected. The JAGI Module takes a single, connected approach to joint, autoimmune, gut, and inflammation health — because in most patients, the real driver of joint degeneration isn't the joint itself.

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Why Chronic Inflammation and Joint Pain Need a New Approach

Standard bloodwork rarely catches the underlying drivers of chronic pain. Increased inflammation and autoimmunity frequently originate in the gastrointestinal system and its microbiome — a connection conventional care rarely tests for, let alone treats. Left unaddressed, that gut-driven inflammation shows up clinically as joint degeneration, or arthritis, long before it's recognized as part of a larger pattern.

Our approach uses in-depth testing to detect:

Autoimmune markers and immune dysregulation

Gut microbiome imbalances and intestinal permeability

Systemic inflammation driving joint and tissue damage

We combine this data with physician-led analysis to create a care plan built around your unique inflammatory and gut-health profile.

What's Included in the JAGI Module

This program is available as a standalone service or as an annual enhancement to the BIOAGE 2026 Program. It includes both in-office and diagnostic lab components.

Biomarker and immune cell line testing to identify states of inflammation and possible autoimmunity
Advanced stool testing to assess gastrointestinal and microbiome health, and other markers of functional gut status
Food sensitivity and allergy panels
Joint-specific imaging (as clinically indicated)

Shockwave therapy
Topical anti-inflammatory patches
Anti-inflammatory injections
PRP (platelet-rich plasma) with exosomes
Autologous MSC (mesenchymal stem cell) therapy
Allogeneic, birth-derived MSC therapy

Joint health currently has the strongest clinical and regulatory support of any application for stem cell technology — the FDA has already cleared its use here, unlike some other indications still confined to research settings.

Initial consultation and diagnostic review
Personalized care plan development
Follow-up visits to monitor progress
Annual reassessment and biomarker retesting

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How MIHA's Approach to Joint Care Is Different

Most joint treatment stops at the joint. At MIHA, the JAGI Module treats joint pain as one symptom of a larger system under strain — a continued source of inflammation or autoimmunity, breaking down tendons and ligaments, alongside sarcopenia (age-related loss of muscle mass). Rather than treating the joint in isolation, JAGI care is built to identify and address that upstream source, so joint therapies have a healthier foundation to work with.

This program is focused on identifying root causes, reducing inflammation, and restoring joint, gut, and immune health — helping you move and feel better long-term.

Benefits may include:

Early detection of autoimmune and inflammatory conditions

Personalized, non-invasive therapy strategies

Better understanding of gut and immune health

Reduced joint pain and improved mobility

A root-cause view that also protects tendons, ligaments, and muscle mass — not just the joint

Reduced reliance on guesswork

Adults dealing with chronic joint pain, autoimmune symptoms, digestive issues, or unexplained systemic inflammation who want to identify root causes rather than just manage symptoms — including those noticing early signs of tendon/ligament wear or muscle loss alongside joint pain.

Frequently Asked Questions About JAGI Module

JAGI stands for Joint, Autoimmune, Gut, and Inflammation. It's the name of MIHA's module for evaluating and treating these four systems together, since in most patients they're driving the same underlying problem rather than acting as separate conditions.

The JAGI Module is MIHA's program for chronic disease outside the three conditions that account for most chronic illness in the industrialized world — cardio-arteriometabolic disease, aberrant cell growth, and neurodegeneration. It focuses on the inflammatory and autoimmune states that cause pain and loss of function, most commonly surfacing as joint degeneration or arthritis.

In many patients, chronic inflammation and autoimmunity originate in the gastrointestinal system and its microbiome. That inflammation doesn't stay contained to the gut — it circulates systemically and frequently shows up as joint degeneration and arthritis, which is why the JAGI Module tests gut health alongside joint-specific markers rather than treating the joint alone.

Testing includes biomarker and immune cell line panels to check for inflammation and possible autoimmunity, advanced stool testing to assess gut and microbiome function, food sensitivity and allergy panels, and joint-specific imaging when clinically indicated.

The JAGI Module offers shockwave therapy, topical anti-inflammatory patches, anti-inflammatory injections, PRP (platelet-rich plasma) with exosomes, and both autologous and allogeneic (birth-derived) mesenchymal stem cell (MSC) therapy, matched to each patient's diagnostic findings.

Autologous MSC therapy uses stem cells drawn from your own body, typically bone marrow or fat tissue. Allogeneic MSC therapy uses birth-derived tissue, such as umbilical cord or Wharton's jelly, from a screened donor. Both are used in the JAGI Module depending on a patient's candidacy and treatment goals.

Joint health is one of the few applications where stem cell technology already has FDA clearance, unlike many other regenerative medicine uses, which remain in research or investigational stages.

A standard joint injection treats the joint in isolation. The JAGI Module treats the joint as part of a larger system — addressing the underlying source of inflammation or autoimmunity, tendon and ligament breakdown, and sarcopenia (muscle loss) that often drive ongoing joint damage, so joint-specific therapies have a healthier foundation to work from.

Adults with chronic joint pain, autoimmune symptoms, digestive issues, or unexplained systemic inflammation are good candidates — especially anyone who has tried treating a joint in isolation without lasting relief, or who is noticing tendon/ligament wear or muscle loss alongside their joint pain.

JAGI Module costs vary widely, typically ranging from around $1,000 to $25,000 or more, depending on which tests and therapies your personalized care plan includes. Baseline testing and therapies such as shockwave therapy, anti-inflammatory injections, or PRP sit toward the lower end of that range, while adding stem cell therapy — autologous or allogeneic MSC — is the main driver of cost at the higher end.

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Find Relief at the Root

You don't need to keep guessing what's driving your pain or discomfort. The JAGI Module gives you a clear, connected path to understanding your joint, gut, and immune health — with expert-guided care.

Take control before symptoms take over.

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In-Person Care in Walnut Creek | Virtual Care Available in San Francisco & Napa